CHIMERAS: MULTI-EPITOPE ANTIGENS
CHIMERAS: MULTI-EPITOPE ANTIGENS
9/9/2019
Figure 1. Chimeras
At Rekom Biotech, we have specialized in the design and production of next-generation antigens: chimeras or antigens composed of multiple epitopes, which have improved their antigenic properties, such as sensitivity and specificity. Furthermore, one main advantage of the multi-epitope chimeric antigens is avoiding the use of protein mixtures in your assay. The limited number of binding sites and the different affinities of proteins for these sites could result in reproducibility issues.
EPITOPE ANALYSIS
SEQUENCE ANALYSIS
3D STUDIES
Rekom Biotech chimeras
|
DISEASE/ALLERGY |
NAME |
REFERENCE |
DESCRIPTION |
|---|---|---|---|
|
Borreliosis or Lyme disease |
RAG0027 (B. burgdorferi, chimera) |
Recombinant chimeric antigen for Borrelia burgdorferi |
|
|
Chagas |
RAG0093 (chimera) |
Recombinant chimeric antigen for Chagas detection |
|
|
RAG0094 (chimera) |
Recombinant chimeric antigen for Chagas detection |
||
|
RAG0096 (chimera) |
Recombinant chimeric antigen for Chagas detection |
||
|
Cytomegalovirus |
ChimCMV1 |
RAG0109 (chimera) |
Recombinant chimeric antigen which contains several antigenic determinants for CMV |
|
ChimCMV2 |
RAG0110 (chimera) |
Recombinant chimeric antigen for CMV detection |
|
|
Syphilis |
ChimSyphilis1 |
RAG0046 (chimera) |
Recombinant chimeric antigen for Treponema pallidum |
|
ChimSyphilis2 |
RAG0064 (chimera) |
Recombinant chimeric antigen for Treponema pallidum |
|
|
Toxoplasmosis |
RAG0058 (chimera) |
Recombinant chimeric antigen ChimToxo1 for toxoplasmosis detection |
|
|
Tuberculosis |
RAG0060 (chimera) |
Recombinant chimeric antigen formed by the proteins CFP10 and ESAT6 |
Written by Ana Camacho.
CATEGORY: SCIENTIFIC NOTES
